N-Nitrosodiethylamine Induced Changes in Levels, Metabolism, and Urinary Excretion of Ascorbic Acid in Guinea Pigs.
نویسندگان
چکیده
منابع مشابه
THE EFFECT OF ASCORBIC ACID ON BLOOD HISTAMINE LEVEL AND DELAYED-TYPE HYPERSENSITIVITY IN GUINEA PIGS
The effect of ascorbic acid on blood histamine level and delayed-type hypersensitivity was studied in thirty male guinea pigs. Animals were sensitized to B.C.G., trichophytin and mallein during the first four weeks. The diet was ad libitum during this period. After this "sensitization period" animals w er e tested intradermally with tuberculin, trichophytin and mallein. The number and diam...
متن کاملAscorbic acid catabolism in guinea pigs.
There have been numerous reports suggesting that the metabolism of ascorbic acid in humans and in animals is affected by stress.l However, detailed information which would permit an analysis of the underlying mechanism is not available. From the variety of effects cited, it would appear that no single mechanism can explain all of the findings. It has been suggested that increased ascorbic acid ...
متن کاملMetabolism of D-ascorbic acid-1-C14 in guinea pigs and rats.
The availability of L-ascorbic acid labeled with Cl4 had made possible studies on the metabolism of the vitamin in man (l), guinea pig (2,3), and rat (4, 5). In the present investigation the metabolic fate of carboxyllabeled n-ascorbic acid and carboxyl-labeled L-ascorbic acid was compared in guinea pigs and rats. This study is of interest, since little is known of the biological fate of D-asco...
متن کاملUrinary excretion and metabolism of procyanidins in pigs
SCOPE Aim of this study was to investigate urinary excretion and metabolism of procyanidins a group of secondary plant metabolites with many beneficial health effects described in literature. METHODS AND RESULTS To investigate the metabolism of procyanidins in the absence of flavan-3-ols, centrifugal partition chromatography was used for their reduction in a grape seed extract to a level of a...
متن کاملAlterations in ascorbic acid transport into the lens of streptozotocin-induced diabetic rats and guinea pigs.
High ascorbic acid (AA) levels in the aqueous humor and intraocular tissues, including the lens, are thought to protect against the harmful effects of photochemical and ambient oxidation reactions involving oxygen and its radicals. In addition, AA may have various metabolic functions, including structural collagen formation in intraocular tissues. Recent work showed that, in the guinea pig, red...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 1991
ISSN: 1880-5086,0912-0009
DOI: 10.3164/jcbn.11.191